Aminocaproic Acid (Generic Amicar) 50ml (250mg/ml) is used to control bleeding and works by affecting the blood clotting system, thereby slowing / stopping bleeding.
Aminocaproic Acid is a derivative and analogue of the amino acid lysine, which makes it an effective inhibitor for enzymes that bind that particular residue. Such enzymes will include proteolytic enzymes like plasmin – the enzyme responsible for fibrinolysis. For this reason aminocaproic acid is effective in treatment of certain bleeding disorders.
Aminocaproic acid is used to treat excessive post-op bleeding, especially after procedures where a great amount of bleeding is expected, such as cardiac surgery. Aminocaproic Acid can be given orally or intravenously. Findings showed that lysine analogs, like aminocaproic acid, significantly reduced blood loss in patients undergoing coronary artery bypass grafting.
Aminocaproic acid is used with heparin therapy in patients with acute promyelocytic leukemia. This use is not currently included in the labeling approved by the US Food and Drug Administration. It is used as initiate therapy when plasma antiplasmin levels have decreased to less than 40% of the normal levels.
Aminocaproic acid is used to control the bleeding that occurs when blood clots are broken down very quickly. This type of bleeding can occur during or after liver or heart surgery, in people who have cancer of the prostate, in people or animals that have certain bleeding disorders, stomach, lung or cervix (and in pregnant women experiencing placental. Aminocaproic acid can also be used to control bleeding in the urinary tract that can occur after kidney or prostate surgery or in people who have certain types of cancer. Aminocaproic acid should not be used to treat bleeding which is not caused by faster than normal clot breakdown. Aminocaproic acid is in the class of medications called hemostatics. AA works by slowing the breakdown of blood clots.
Dosage and Administration: Administer 10-20ml by intravenous injection 3-6 hours before event.