GLUCOSAMINE 100 ml: Anti-Inflammatory, Anti-Arthritic & Chondroprotective Agent for IV Use in Horses.
COMPOSITION: Contains: GLUCOSAMINE HYDROCHLORIDE 200 mg/ml
ACTIONS: Glucosamine is utilized in the production of glycosaminoglycans (GAGs) which then combine with hyaluronic acid (HA) to form large proteoglycans in the matrix of cartilage. As such, glucosamine is a fundamental molecule for the synthesis and the structure of cartilage. A growing body of evidence supports the pain relieving and potentially chondroprotective properties of glucosamine. Notably, glucosamine prevents the degradation of cartilage proteoglycans in vitro and also regulates the production of proteoglycan by chondrocytes. Glucosamine has also been shown in vitro to protect against the inhibition of proteoglycan production in chondrocytes caused by methylprednisolone.
Oral administration of glucosamine and chondroitin sulfate has demonstrated positive effects on equine osteoarthritis and intravenous administration of glucosamine more rapidly produces significantly higher serum and synovial fluid glucosamine levels. During one twelve hour study period, intravenous administration in horses created maximum glucosamine levels 50 times higher in the serum and over 20 times higher in the synovial (joint) fluid than via oral administration of the same glucosamine HCl dose.
In Australian trials of GLUCOSAMINE HYDROCHLORIDE 200 mg/ml, veterinarians reported “Good” to “Very Good” response in 67.5% of the osteoarthritic horses treated (20mL IV daily for 5 – 10 days in most cases). Positive responses have included improved action and race performance and reduced lameness and joint effusion.
Pentosan polysulfate, as contained in Racehorse Meds PENTOSAN, PENTOSAN PLATINUM and PENTOSAN GOLD are known to stimulate cartilage healingâ€¦ a process which utilizes glucosamine for production of GAGs and HA. Combining glucosamine injections prior to and/or at the time of PENTOSAN INJECTION or PENTOSAN GOLD administration, may enhance the beneficial effects on the joints.
INDICATIONS: For use in selected cases to help improve joint function in horses.
FORM: Sterile for injection
FOR: Horses, Dogs and Camels
DOSAGE & ADMINISTRATION:
Adult Horses: Administer 20 ml daily by intravenous (IV) injection for 5-10 days In light of the actions of glucosamine discussed above, consideration may also be given to:
– Protective pre-treatment with Racehorse Meds GLUCOSAMINE Injection prior to intra-articular corticosteroid injections;
– Adjunctive pre- or concurrent treatment with Racehorse Meds GLUCOSAMINE Injection for PENTOSAN INJECTION or PENTOSAN GOLD injections.
STORAGE: Storage: Store below 25C (Air Conditioning) and protect from light.
NOTE: This product can be used with any other Vitamin or supplement from Racehorse Meds.
For use as a supplemental source of Vitamins & Amino Acids in horses, cattle, sheep, swine, camels, alpacas and pigeons. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.