Glycopyrrolate (Generic Robinul) 0.2mg/ml 20ml

$11.99

99864 in stock

Description

Glycopyrrolate (Generic Robinul) 20ml (0.2mg/ml)

Glycopyrrolate is used to reduce secretions in the airway, mouth, throat and stomach.

CLINICAL PHARMACOLOGY:

Glycopyrrolate, like other anticholinergic (antimuscarinic) agents, inhibits the action of acetylcholine on structures innervated by postganglionic cholinergic nerves and on smooth muscles that respond to acetylcholine but lack cholinergic innervation. These peripheral cholinergic receptors are present in the autonomic effector cells of smooth muscle, cardiac muscle, the sinoatrial node, the atrioventricular node, exocrine glands and, to a limited degree, in the autonomic ganglia. Thus, it diminishes the volume and free acidity of gastric secretions and controls excessive pharyngeal, tracheal, and bronchial secretions.

Glycopyrrolate antagonizes muscarinic symptoms (e.g., bronchorrhea, bronchospasm, bradycardia, and intestinal hypermotility) induced by cholinergic drugs such as the anticholinesterases.

The highly polar quaternary ammonium group of glycopyrrolate limits its passage across lipid membranes, such as the blood-brain barrier, in contrast to atropine sulfate and scopolamine hydrobromide, which are highly non-polar tertiary amines which penetrate lipid barriers easily.

With intravenous , the onset of action is generally evident within one minute. Following intramuscular administration, the onset of action is noted in 15 to 30 minutes, with peak effects occurring within approximately 30 to 45 minutes. The vagal blocking effects persist for 2 to 3 hours and the antisialagogue effects persist up to 7 hours, periods longer than for atropine.

Dosage and Administration:  Administer 5ml by intravenous or intramuscular as needed.

STORAGE: Storage:  Store below 25C (Air Conditioning) and protect from light.

Glycopyrrolate will test in many jurisdictions.  Check your local rules.

Reviews

There are no reviews yet.

Be the first to review “Glycopyrrolate (Generic Robinul) 0.2mg/ml 20ml”