RESERPINE (Compare to the active ingredients of Nature Vet Rakelin®) is a long-acting non-sedating injectable calmative agent.
COMPOSITION: Contains: Reserpine 0.5 mg/ml
ACTION:- RESERPINE causes a rapid release of the nerve system transmitters serotonin and norepinephrine from bound stores in the brain, subjecting them to rapid destruction by the body’s own enzyme, monoamine oxidase (MOA). While “bound”, the stores are not available to MOA. Serotonin and norepinephrine have potent effects on the metabolism of the brain. Higher levels (especially of norepinephrine) cause stimulation of cerebral activity and anxiety. L owered levels depress cerebral activity resulting in relaxation and calmness. Serotonin and norepinephrine, on release from the bound stores, undergo rapid destruction by MOA. The net depletion of these substances creates the calming and relaxing effects of RESERPINE . These effects continue for many days after administration, because levels are restored slowly.
INDICATION: RESERPINE is particularly indicated where a prolonged effect to reduce anxiety and/or to calm horses is required, especially in the handling and management of dangerously anxious horses. RESERPINE is useful as an aid when unfamiliar surroundings and/or unaccustomed stress create anxiety in horses and also as a calming agent to aid in the training and education of stressed young horses. RESERPINE produces a prolonged calming effect without sedation, drowsiness, or loss of coordination while vicious or dangerously anxious horses will become relaxed, sociable and co-operative with continued treatment. RESERPINE is indicated in any situation where stress or anxiety in horses is difficult to manage. Before using on horses that will be involved in competitive activities, the pre-competition withdrawal period should be ascertained (this may vary from one juristiction to another depending on laboratory methods used for substance detection).
FOR: Horses, Dogs and Camels.
DOSAGE & ADMINISTRATION:
Administer RESERPINE by intramuscular (IM) only. The dose administered must be sufficient to deplete Serotonin and Norepinephrine stores. Because the initial levels of these stores will vary from horse to horse, the veterinarian must be prepared to vary the dose to achieve optimum efficacy. A useful clinical sign is abrief period of diarrhea, which accompanies the initial release of bound Serotonin before its destruction by MOA. This period of increased bowel activity is a reliable indicator that the desired behavioral response should follow.
Adult Horses: Administer 1ml to 4ml by intramuscular weekly or as directed by a veterinary surgeon. Administer by intramuscular ONLY. Some veterinarians advise giving 2-4ml on alternate days until desired response is achieved. Repeat s of 2 to 4ml at 4 to 8 day intervals. This dosage regime may be altered to suit the individual animal response. Lack of response is almost always the result of under dosing.
STORAGE – Store below 25C (Air Conditioning) and protect from light.
NOTE: This product can be used with any other Vitamin or supplement from Racehorse Meds. This product is best used the day before and the day of event BUT MAY TEST IN SOME JURISDICTIONS. CHECK WITH YOUR LOCAL RULES This product compares to Nature Vet® Rakelin® in that both have the same ingredients. This product is not manufactured or distributed by Nature Vet® who is the sole distributor of Rakelin®
WARNING: RESERPINE may produce penile relaxation. Stallions which have been treated with RESERPINE (Compare to the active ingredients of Nature Vet Rakelin®) should not be used to service mares for at least fourteen days following .
For use as a supplemental source of Vitamins & Amino Acids in horses, cattle, sheep, swine, camels, alpacas and pigeons. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.